• Skip to primary navigation
  • Skip to main content
  • Skip to footer
Show Search
Home
EN / FR
  • LinkedIn
  • Twitter
Celyad Oncology

Celyad Oncology

  • About Us
    • Overview
    • Management Team
    • Board Of Directors
    • Partners
  • Science
    • Overview
    • Approach
    • Technology
      • TIM
      • shRNA
    • Manufacturing
    • Scientific Publications
  • Pipeline
  • Newsroom
    • Press Releases
    • Events
    • Media Center
  • Investors
    • Overview
    • Analyst Coverage
    • Corporate Governance
    • Regulated Information
    • Shareholders Information
    • Shareholders Meeting
  • Careers
  • Contact Us
Home / Science / All-In-One Vector

All-In-One Vector

All-in-One Vector Approach

Celyad Oncology focuses on using a single vector approach to generate CAR T cells

Encoding multiple components of the CAR T construct, including the chimeric antigen receptor T (CAR T) cell selection marker (e.g. truncated CD19), therapeutic add-ons (e.g. cytokines), non-gene edited allogeneic technology (i.e. TIM or short hairpin RNAs (shRNAs)) in a single vector helps Celyad Oncology to simplify the design and development of our cell therapy candidates.

 

RGB_All-In-One Vector

This single transduction, plug and play approach to CAR T development also helps to streamline process development and manufacturing while broadening the potential applicability of our candidates.

When coupled with our allogeneic platforms, including both our TIM and shRNA technologies, the All-in-One Vector approach avoids multiple genetic modifications and costs associated with additional Good Manufacturing Practice (GMP) grade vectors. In addition, when combined with our shRNA technology, the single vector approach demonstrates efficient expression of multiple shRNAs and enables the generation of a homogenous CAR T cell population through a single step enrichment.

 

LEARN ABOUT OUR TECHNOLOGY

Footer

  • About
  • Science
  • Pipeline
  • Newsroom
  • Investors
  • Contact Us
  • LinkedIn
  • Twitter

Copyright © 2020 All Rights Reserved.
Cookie Policy | Privacy Policy | Terms of Use