Celyad Oncology is looking for a R&D Technician. The successful candidate will be based in Belgium (Mont-Saint-Guibert). The R&D Technician reports to the R&D Lab Manager. He/she participates in the planning, execution and analysis of specific scientific experiments related to the translation of basic research into clinical development. The R&D Technician provides support to the R&D Department and works closely with the R&D Scientists to fulfill the R&D objectives.  

Role & Responsibilities

• Perform experiments timely and with high accuracy according to Celyad Oncology quality standards.
• To be involved in the production and optimization of CAR T cells.
• To be involved in the development/validation of methods aimed at characterizing therapeutics that form the core focus of the R&D Department.
• To contribute to the laboratory maintenance activities, including logistics, managing of stocks and inventories and maintenance of equipment.
• To ensure traceability of data and operations
• Support R&D scientists with preparation of protocols, planning and analysis of experiments.
• Keep up with scientific background on personal project(s) through pro-active communication with scientists and participation in scientific meetings.
• Maintain high standards in lab ethics.
• To take part in weekend rotation (max 1 WE/ 2 months)

 

Qualifications & Experience

• Bachelor or master’s degree in Biological sciences.
• Relevant experience in research within Biotech/Pharma industry is a plus.
• Relevant experience in standard cellular and molecular biology techniques such as DNA cloning, gene expression analysis, gene transfer (e.g. retrovirus, lentivirus), (primary) cell culture, multi-color flow cytometry and ELISA is a plus.
• Good knowledge of common computer software packages (Windows, MS Office, etc.)
• Good knowledge of English and French.

 

Skills & Competencies

• Deliver results and commit to achieve challenging objectives
• Self-motivated and enthusiastic personality
• Good planning & organizational skills
• Team player
• Flexibility and can-do attitude
• Problem solving, proactive
• Quality Mindset
• Integrity & Trust

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The successful candidate will be based in Belgium and will report into the Head of Clinical Operations in Mont-Saint-Guibert.

Role:

The (Senior) CRA will strengthen our team within Clinical Operations Department, supporting our many projects. As an experienced professional with a complete understanding and wide application of principle, theories, and concepts in the field of clinical research, you will be a productive member of the team. You enjoy start up, enrollment, follow up and closure of clinical trial activities, and mainly monitoring the progress of clinical studies at the site level.

Responsibilities:

• Clinical Site Start-up :
  • Support with identification of clinical sites
  • Preparation of packages for ethical committee (EC) submissions
  • Submissions to ECs
  • Preparation of site budget, negotiations of site budget
  • Organization, preparation, performance, follow-up of Site Qualification visits, Site Initiation visits
• Clinical Site Management :
  • Organization, performance, follow-up of trainings
  • Organization, preparation, performance, follow-up of Monitoring visits, Close-out visits
  • Identification, communication, resolution of site-related matters, issue escalation
  • Site leadership
• Development, writing, review of task-related SOPs
• Support clinical supply chain

Qualifications & Experience

• Bachelor or Master degree in (para-) medical or scientific field
• Involvement in study start-up and EC submissions in at least 2 countries
• At least 7 years of clinical research experience including monitoring, or in pharmaceutical data management including activities during data base locks, or as a study coordinator
• Experience with oncology in early phases
• Experience with Advanced Therapy Medicinal Products (ATMPs) is an advantage

Skills & Competencies

• Very strong attention to details
• Work precisely as per procedures, rules and regulations
• Objective and analytical
• Planning & Organizing skills
• Team spirit
• Excellent English, French and Dutch knowledge (“trilingual”, oral and written), additional languages are an asset
• Strong communication skills
• Hands-on attitude

For more information about this position or about the Company, please contact us by email at  job@celyad.com

 

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The successful candidate will be based in Belgium (Mont-Saint-Guibert).

Role & Responsibilities

• Work within a dedicated discovery research team focused upon delivering key readouts from the company’s new technological advances and cutting-edge products that will form the basis of the company’s core research and clinical strategy.
• Design, plan and perform scientific research on early stage immune oncology discovery programs, to design, create, and characterize the next generation of CARs.
• Work on novel, testable hypotheses to expand our understanding of CAR T cell biology and structure/function relationship.
• Generate scientific proposals and resolve key project hurdles with available information from literature and internal experts.
• Actively participate in and be fully cognizant of practical laboratory work involving the core activities of the discovery research group and work closely with technical staff providing guidance in the delivery of the research readouts.
• Develop and maintain a deep knowledge of relevant scientific literature concerning new research and technologies within the scientific field of Celyad Oncology.
• Ensure good traceability of operations, using appropriate records and templates.
• Present data to project group and larger multidisciplinary teams including externally at meetings/congresses/conferences and author publications in peer-reviewed scientific journals.
• Maintain open and effective communication with R&D Scientists and the different departments of the company in collaborative projects through means including reports and presentations.

Qualifications & Experience

• PhD in biological sciences with emphasis on molecular biology or genetics
• Minimum 3 years post-doctoral experience with a publication track record in high quality peer-reviewed scientific journals
• Expertise in molecular biology, cloning, gene expression, retroviral/lentiviral gene delivery and gene editing.
• Experience in immunology (T cell culture, cytokine analysis, proliferation, cytotoxicity) is a big plus.
• Excellent communications skills in English, both written and verbal are required.

 

Skills & Competencies

• Self-motivated and enthusiastic personality
• Strong ability to work in a team focused upon the delivery of results that support the company’s objectives.
• Deliver results and commit to achieve challenging objectives
• Problem solving, proactive
• Scientific writing and presentation skills
• Good planning & organizational skills
• Flexibility and can-do attitude
• Integrity & Trust

For more information about this position or about the Company, please contact us by email at  job@celyad.com

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• Select and activate chosen study sites, establish and maintain an excellent relationship with site investigators and research teams
• Create and update activities in overall project plan on a regular basis to assure appropriate outcome of clinical trial projects in terms of scope, timelines and objectives.
• Coordination of assigned CRA monitoring activities
• Ensure study quality/GCP compliance to deliver a rigorous patient data
• Partner with Clin Ops Director and provide oversight to all vendors or study delivery team, ensuring timely delivery of milestones and budget compliancy
• Propose and implement study process improvements; Participate in the preparation, updating and training of SOPs
• Liaise with manufacturing, central lab, and other study project stakeholders as needed
• Prepares all external and internal documentation for assigned trials ensuring it is completed in accordance with the study protocol, internal SOP’s and GCP requirements (e.g., Patient Informed Consent Forms, Monitoring Plans, Project Plans)
• Works with the Clin Ops Team to develop and maintain study timelines
• Responsible for ensuring vendors deliver according to scope of work and review/approve vendor invoices

• Degree in Life Science, biological science, or related area: or equivalent relevant experience acquired within life science industries
• At least 10 years’ experience in clinical project management, including early phase
• Therapeutic area of expertise in oncology/haematology trials is highly desirable
• Prior Biotech experience is highly desirable
• Strong knowledge of ICH and GCP rules and of the complete clinical trials process

• Creative and finding ways to get the job done
• Thriving in challenging environments and finds ways to remove obstacles to complete enrollment and deliver a robust patient data package
• Flexible mindset capable to manage change and deal with ambiguity
• Proven ability to manage complex projects
• Flexibility to re-prioritize workload to meet changing timelines
• Excellent communicator able to raise the profile of clinical studies within sites and create advocates for recruitment
• Autonomous, pro-active and hands on personality.
• Driven to achieving highest results in challenging timeframe
• Efficient in planning and executing work: orchestrate multiple activities at once
• Team player, able to navigate thru a matrix organization in multi-cultural environment
• Driven to achieving highest results in challenging timeframe
• Efficient in planning and executing work: orchestrate multiple activities at once
• Team player, able to navigate thru a matrix organization in multi-cultural environment

For more information about this position or about the Company, please contact us by email at job@celyad.com

Apply for THIS POSITION